Timothy McKinsey : rechercher sur Z-Library

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1

Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface

McKinsey, Timothy A., Kass, David A.

Journal:

Nature Reviews Drug Discovery

Année:

2007

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2007

2

Therapeutic Potential for HDAC Inhibitors in the Heart

McKinsey, Timothy A.

Journal:

Annual Review of Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 710 KB

english, 2012

3

A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium

Sucharov, Carmen C., Nakano, Stephanie J., Slavov, Dobromir, Schwisow, Jessica A., Rodriguez, Erin, Nunley, Karin, Medway, Allen, Stafford, Natalie, Nelson, Penny, McKinsey, Timothy A., Movsesian, Mat

Journal:

Journal of the American College of Cardiology

Année:

2019

Langue:

english

Fichier:

PDF, 863 KB

english, 2019

4

A high-performance liquid chromatography assay for quantification of cardiac myosin heavy chain isoform protein expression

Douglas D. Lemon, Philip J. Papst, Kristin Joly, Craig F. Plato, Timothy A. McKinsey

Journal:

Analytical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 449 KB

english, 2011

5

10.1038/35040593

Olson, Eric N., McKinsey, Timothy A., Zhang, Chun-Li, Lu, Jianrong

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 396 KB

english, 2000

6

10.1038/81321

Olson, Eric N., Frey, Norbert, McKinsey, Timothy A.

Journal:

Nature Medicine

Année:

2000

Langue:

english

Fichier:

PDF, 236 KB

english, 2000

7

A threshold nuclear level of the v-Rel oncoprotein is required for transformation of avian lymphocytes

Sachdev, Shrikesh, Diehl, J Alan, McKinsey, Timothy A, Hans, Alexandra, Hannink, Mark

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 502 KB

english, 1997

8

NF-κB is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis

Jo, Hakryul, Zhang, Rong, Zhang, Hong, McKinsey, Timothy A, Shao, Jinyi, Beauchamp, R Daniel, Ballard, Dean W, Liang, Peng

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 650 KB

english, 2000

9

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

Lauren Monovich, Richard B. Vega, Erik Meredith, Karl Miranda, Chang Rao, Michael Capparelli, Douglas D. Lemon, Dillon Phan, Keith A. Koch, Joseph A. Chapo, David B. Hood, Timothy A. McKinsey

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2010

10

Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases

Brooke C. Harrison, Khai Huynh, Greta L. Lundgaard, Steven M. Helmke, M. Benjamin Perryman, Timothy A. McKinsey

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2010

11

Cardiac histone acetylation – therapeutic opportunities abound

Timothy A McKinsey, Eric N Olson

Journal:

Trends in Genetics

Année:

2004

Langue:

english

Fichier:

PDF, 720 KB

english, 2004

12

Signaling chromatin to make muscle

Timothy A McKinsey, Chun Li Zhang, Eric N Olson

Journal:

Current Opinion in Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 354 KB

english, 2002

13

MEF2: a calcium-dependent regulator of cell division, differentiation and death

Timothy A McKinsey, Chun Li Zhang, Eric N Olson

Journal:

Trends in Biochemical Sciences

Année:

2002

Langue:

english

Fichier:

PDF, 160 KB

english, 2002

14

Increased Phosphorylation-Dependent Nuclear Export of Class II Histone Deacetylases in Failing Human Heart

Mihail B. Calalb, Timothy A. McKinsey, Scott Newkirk, Khai Huynh, Carmen C. Sucharov, Michael R. Bristow

Journal:

Clinical and Translational Science

Année:

2009

Langue:

english

Fichier:

PDF, 2.94 MB

english, 2009

15

Protein kinase D directly phosphorylates histone deacetylase 5 via a random sequential kinetic mechanism

Q. Khai Huynh, Timothy A. McKinsey

Journal:

Archives of Biochemistry and Biophysics

Année:

2006

Langue:

english

Fichier:

PDF, 218 KB

english, 2006

16

A novel protein kinase C target site in protein kinase D is phosphorylated in response to signals for cardiac hypertrophy

Dillon Phan, Matthew S. Stratton, Q. Khai Huynh, Timothy A. McKinsey

Journal:

Biochemical and Biophysical Research Communications

Année:

2011

Langue:

english

Fichier:

PDF, 806 KB

english, 2011

17

β-Adrenergic Receptor Stimulation and Activation of Protein Kinase A Protect Against α1-Adrenergic–Mediated Phosphorylation of Protein Kinase D and Histone Deacetylase 5

Carmen C. Sucharov, Karen Dockstader, Karin Nunley, Timothy A. McKinsey, Michael Bristow

Journal:

Journal of Cardiac Failure

Année:

2011

Langue:

english

Fichier:

PDF, 682 KB

english, 2011

18

Isoform-selective HDAC inhibitors: Closing in on translational medicine for the heart

Timothy A. McKinsey

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2011

Langue:

english

Fichier:

PDF, 545 KB

english, 2011

19

Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension

Douglas D. Lemon, Todd R. Horn, Maria A. Cavasin, Mark Y. Jeong, Kurt W. Haubold, Carlin S. Long, David C. Irwin, Sylvia A. McCune, Eunhee Chung, Leslie A. Leinwand, Timothy A. McKinsey

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2011

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2011

20

Class II Histone Deacetylases Act as Signal-Responsive Repressors of Cardiac Hypertrophy

Chun Li Zhang, Timothy A. McKinsey, Shurong Chang, Christopher L. Antos, Joseph A. Hill, Eric N. Olson

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 581 KB

english, 2002

21

Transcription factor NF-κB regulates inducible CD83 gene expression in activated T lymphocytes

Timothy A. McKinsey, Zhi-Liang Chu, Thomas F. Tedder, Dean W. Ballard

Journal:

Molecular Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 240 KB

english, 2000

22

Control of muscle development by dueling HATs and HDACs

Timothy A McKinsey, Chun Li Zhang, Eric N Olson

Journal:

Current Opinion in Genetics & Development

Année:

2001

Langue:

english

Fichier:

PDF, 237 KB

english, 2001

23

Cardiac hypertrophy, sorting out the circuitry

Timothy A McKinsey, Eric N Olson

Journal:

Current Opinion in Genetics & Development

Année:

1999

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1999

24

Regulation of Skeletal Myogenesis by Association of the MEF2 Transcription Factor with Class II Histone Deacetylases

Jianrong Lu, Timothy A. McKinsey, Chun-Li Zhang, Eric N. Olson

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 411 KB

english, 2000

25

Novel serotonergic modulators of cardiac hypertrophy

Erik W. Bush, Jens Fielitz, Lawrence Melvin, Michael Arnold-Martinez, Timothy A. McKinsey, Ryan Plichta, Eric N. Olson

Journal:

Journal of Cardiac Failure

Année:

2004

Langue:

english

Fichier:

PDF, 56 KB

english, 2004

26

A novel phospho-acceptor site controls nuclear import of histone deacetylase 9, a negative regulator of pathological cardiac hypertrophy

Brooke C. Harrison, Shurong Chang, Steve M. Helmke, Igor I. Rybkin, Benjamin Perryman, Eric N. Olson, Timothy A. McKinsey

Journal:

Journal of Cardiac Failure

Année:

2004

Langue:

english

Fichier:

PDF, 77 KB

english, 2004

27

Protein kinases C and D target class II histone deacetylases to control pathological cardiac gene expression

Brooke C. Harrison, Rick B. Vega, Eric N. Olson, Timothy A. McKinsey

Journal:

Journal of Cardiac Failure

Année:

2004

Langue:

english

Fichier:

PDF, 83 KB

english, 2004

28

Differential effects of histone deacetylase inhibitors on hypertrophic signaling pathways

Hansjorg Rindt, Matthew Dreitz, Lisa Hollingsworth, David Hood, Erik Bush, Brooke Harrison, Timothy McKinsey

Journal:

Journal of Cardiac Failure

Année:

2004

Langue:

english

Fichier:

PDF, 59 KB

english, 2004

29

Hypoxia Alters Ocular Drug Transporter Expression and Activity in Rat and Calf Models: Implications for Drug Delivery

Kadam, Rajendra S., Ramamoorthy, Preveen, LaFlamme, Daniel J., McKinsey, Timothy A., Kompella, Uday B.

Journal:

Molecular Pharmaceutics

Année:

2013

Langue:

english

Fichier:

PDF, 2.62 MB

english, 2013

30

BET acetyl-lysine binding proteins control pathological cardiac hypertrophy

Spiltoir, Jessica I., Stratton, Matthew S., Cavasin, Maria A., Demos-Davies, Kim, Reid, Brian G., Qi, Jun, Bradner, James E., McKinsey, Timothy A.

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2013

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2013

31

Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes

Williams, Sarah M., Golden-Mason, Lucy, Ferguson, Bradley S., Schuetze, Katherine B., Cavasin, Maria A., Demos-Davies, Kim, Yeager, Michael E., Stenmark, Kurt R., McKinsey, Timothy A.

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 2.46 MB

english, 2014

32

Targeting cardiac fibroblasts to treat fibrosis of the heart: Focus on HDACs

Schuetze, Katherine B., McKinsey, Timothy A., Long, Carlin S.

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 772 KB

english, 2014

33

BET-ting on chromatin-based therapeutics for heart failure

Haldar, Saptarsi M., McKinsey, Timothy A.

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 366 KB

english, 2014

34

Proteomic Profile of Lipid Peroxidation in Human Cardiomyopathy

Fritz, Kristofer S, Blakeslee, Weston, McKinsey, Timothy A, Petersen, Dennis R

Journal:

Free Radical Biology and Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 204 KB

english, 2012

35

Suppression of Tumor Necrosis Factor-Induced Cell Death by Inhibitor of Apoptosis c-IAP2 is under NF-κ B Control

Zhi-Liang Chu, Timothy A. McKinsey, Lily Liu, Jennifer J. Gentry, Michael H. Malim and Dean W. Ballard

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 1.62 MB

english, 1997

36

Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism

Blakeslee, Weston W., Wysoczynski, Christina L., Fritz, Kristofer S., Nyborg, Jennifer K., Churchill, Mair E.A., McKinsey, Timothy A.

Journal:

Cellular Signalling

Année:

2014

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2014

37

Regulation of Aberrant Expression of EC-SOD in Human IPAH by Epigenetic Mechanisms

Woods, Crystal, Venkataraman, Sujatha, Stearman, Robert, Mouradian, Gary, Villegas, Leah, Bowler, Russell, McKinsey, Timothy, Ferguson, Bradley, Ihida-Stansbury, Kaori, Geraci, Mark, Stenmark, Kurt, D

Journal:

Free Radical Biology and Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 73 KB

english, 2014

38

Targeting histone deacetylases for heart failure

Bush, Erik W, McKinsey, Timothy A

Journal:

Expert Opinion on Therapeutic Targets

Année:

2009

Langue:

english

Fichier:

PDF, 711 KB

english, 2009

39

Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy

McLendon, Patrick M., Ferguson, Bradley S., Osinska, Hanna, Bhuiyan, Md. Shenuarin, James, Jeanne, McKinsey, Timothy A., Robbins, Jeffrey

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2014

40

Suppression of pathological cardiac fibrosis by histone deacetylase inhibitors

Schuetze, Katherine B., McKinsey, Timothy A.

Journal:

Progress in Pediatric Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 111 KB

english, 2014

41

Reversal of severe angioproliferative pulmonary arterial hypertension and right ventricular hypertrophy by combined phosphodiesterase-5 and endothelin receptor inhibition

Cavasin, Maria A, Demos-Davies, Kimberly M, Schuetze, Katherine B, Blakeslee, Weston W, Stratton, Matthew S, Tuder, Rubin M, McKinsey, Timothy A

Journal:

Journal of Translational Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2014

42

Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscle

Lemon, Douglas D., Harrison, Brooke C., Horn, Todd R., Stratton, Matthew S., Ferguson, Bradley S., Wempe, Michael F., McKinsey, Timothy A.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2015

43

Acetyl-lysine erasers and readers in the control of pulmonary hypertension and right ventricular hypertrophy 1

Stratton, Matthew S., McKinsey, Timothy A.

Journal:

Biochemistry and Cell Biology

Année:

2015

Fichier:

PDF, 976 KB

2015

44

Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement

Salian-Mehta, Smita, Xu, Mei, McKinsey, Timothy A., Tobet, Stuart, Wierman, Margaret E.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2015

45

Non-sirtuin histone deacetylases in the control of cardiac aging

Ferguson, Bradley S., McKinsey, Timothy A.

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2015

Langue:

english

Fichier:

PDF, 449 KB

english, 2015

46

Emerging roles for histone deacetylases in pulmonary hypertension and right ventricular remodeling (2013 Grover Conference series)

Cavasin, Maria A., Stenmark, Kurt R., McKinsey, Timothy A.

Journal:

Pulmonary Circulation

Année:

2015

Langue:

english

Fichier:

PDF, 771 KB

english, 2015

47

Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change

Stenmark, KurtR, Frid, MariaG, Yeager, Michael, Li, Min, Riddle, Suzette, McKinsey, Timothy, El Kasmi, KarimC

Journal:

Pulmonary Circulation

Année:

2012

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2012

48

Retraction of “Hypoxia Alters Ocular Drug Transporter Expression and Activity in Rat and Calf Models: Implications for Drug Delivery”

Kadam, Rajendra S., Ramamoorthy, Preveen, LaFlamme, Daniel J., McKinsey, Timothy A., Kompella, Uday B.

Journal:

Molecular Pharmaceutics

Année:

2015

Langue:

english

Fichier:

PDF, 114 KB

english, 2015

49

Transgenic over-expression of YY1 induces pathologic cardiac hypertrophy in a sex-specific manner

Stauffer, Brian L., Dockstader, Karen, Russell, Gloria, Hijmans, Jamie, Walker, Lisa, Cecil, Mackenzie, Demos-Davies, Kimberly, Medway, Allen, McKinsey, Timothy A., Sucharov, Carmen C.

Journal:

Biochemical and Biophysical Research Communications

Année:

2015

Langue:

english

Fichier:

PDF, 637 KB

english, 2015

50

High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling

Zhao, Yuanbiao, Londono, Pilar, Cao, Yingqiong, Sharpe, Emily J., Proenza, Catherine, O’Rourke, Rebecca, Jones, Kenneth L., Jeong, Mark Y., Walker, Lori A., Buttrick, Peter M., McKinsey, Timothy A., S

Journal:

Nature Communications

Année:

2015

Langue:

english

Fichier:

PDF, 2.54 MB

english, 2015